Arsenal are out of the Checkatrade Trophy after losing 6-2 to Cheltenham Town.
The Gunners were reduced to 10 men seven minutes in as Robbie Burton was sent off by referee Stephen Martin.
By half-time the game hung in the balance with a score of 2-1 with 17-year-old striker Tyreece John-Jules finding the back of the net to pull one back for the visitors.
He danced around the goalkeeper to slot home his shot and later won a penalty that was dispatched by Charlie Gilmour.
London interest was also focused on Chelsea’s on-loan youngster Jacob Maddox who enjoyed a landmark evening to punish his parent club’s Premier League rivals.
It was his work on the edge of the Arsenal box that drew the foul that saw Burton given his marching orders.
The 19-year-old then scored twice in the second half – the first senior goals of his career.
Midfielder Ben Sheaf went close with a freekick but shot wide as Cheltenham made the most of their numerical advantage to pull ahead of their young opponents.
By the final whistle, Arsenal’s Under 21s had been knocked out the Checkatrade Trophy in a 6-2 defeat.
Iliev; Olayinka, Medley (Bramall 90), Ballard Bola; Burton, Gilmour, Sheaf (Smith 28); Coyle, John-Jules, Saka. Subs not used: Bramall, Thompson, Tormey, Zelalem, Balogun, Hein